Tumor microenvironment - TME

Sensitivity to immune checkpoint inhibitors in BRAF/MEK inhibitor refractory melanoma
Riyaben P Patel, Lydia Rui Jia Lim, Reem Saleh, Darius Schenk, Michael K Lee, Emily Lelliott, Aparna D Rao, Shaghayegh Arabi, Lorey Smith, Anna S Trigos, Nicole Haynes, Grant A McArthur, Karen E Sheppard

Journal for ImmunoTherapy of Cancer May 2025, 13 (5) e011551; DOI: 10.1136/jitc-2025-011551
GP73: the key to unlocking immunotherapies efficacy in solid tumors?
Rebecca J Bayliss, Alan L Parker

Journal for ImmunoTherapy of Cancer May 2025, 13 (5) e011989; DOI: 10.1136/jitc-2025-011989
Spatial transcriptomics highlights B cells as key contributors to a complete and durable response to chemo-immunotherapy in a patient with resectable NSCLC
Nicla Porciello, Filippo Gallina, Giuseppe Frisullo, Francesca Fusco, Lorenzo D’Ambrosio, Vittoria Balzano, Francesca De Nicola, Paolo Visca, Lorenza Landi, Federico Cappuzzo, Paola Nistico

Journal for ImmunoTherapy of Cancer May 2025, 13 (5) e011563; DOI: 10.1136/jitc-2025-011563
Defects in the necroptosis machinery are a cancer resistance mechanism to checkpoint inhibitor immunotherapy
Anna Sax, Peter May, Stefan Enssle, Nardine Soliman, Tatiana Nedelko, Giada Mandracci, Fabian Stögbauer, Laura Joachim, Christof Winter, Florian Bassermann, Katja Steiger, Nadia El Khawanky, Hendrik Poeck, Simon Heidegger

Journal for ImmunoTherapy of Cancer May 2025, 13 (5) e010433; DOI: 10.1136/jitc-2024-010433
Dual role of Metrnl: exercise-induced benefits and potential cancer implications
Hamid Alizadeh

Journal for ImmunoTherapy of Cancer May 2025, 13 (5) e011666; DOI: 10.1136/jitc-2025-011666
B4GALT5 inhibits CD8⁺ T-cell response by downregulating MHC-I level through ERAD pathway in PDAC
Xin Xing, Shi-Qi Yin, Xia-Qing Li, Hui Li, Hong-Tai Ma, Aziguli Tulamaiti, Shu-Yu Xiao, Yu-Tong Liu, Hao Zhang, Zhigang Zhang, Yan-Miao Huo, Xiao-Mei Yang, Yan Yang, Xue-Li Zhang

Journal for ImmunoTherapy of Cancer May 2025, 13 (5) e010908; DOI: 10.1136/jitc-2024-010908
Targeting nerve growth factor: an Achilles’ heel for tumors?
Elizabeth Repasky, Hemn Mohammadpour

Journal for ImmunoTherapy of Cancer May 2025, 13 (5) e011609; DOI: 10.1136/jitc-2025-011609
Tumor-infiltrating mast cells as potential chemoimmunotherapy enhancer in triple-negative breast cancer
Pinchao Fan, Chengjun Zhu, Xiaoxiang Guan

Journal for ImmunoTherapy of Cancer Apr 2025, 13 (4) e011899; DOI: 10.1136/jitc-2025-011899
Novel PD-1-targeted, activity-optimized IL-15 mutein SOT201 acting in cis provides antitumor activity superior to PD1-IL2v
Hana Matuskova, Pavel Marasek, Vladyslav Mazhara, Ekaterina Simonova, Lucie Kosinova, Petr Danek, Klara Danova, Katerina Sajnerova, Iva Malatova, Klara Hrabankova, Denise Greco, Ondrej Martinec, Matej Fabisik, Nada Podzimkova, Kamila Hladikova, Katerina Behalova, Zuzana Antosova, Milada Sirova, Romana Mikyskova, Milan Reinis, Marek Kovar, David Béchard, Ulrich Moebius, Lenka Palova Jelinkova, Radek Spisek, Martin Steegmaier, Irena Adkins

Journal for ImmunoTherapy of Cancer Apr 2025, 13 (4) e010736; DOI: 10.1136/jitc-2024-010736
Neural crest-associated gene FOXD1 induces an immunosuppressive microenvironment by regulating myeloid-derived suppressor cells in melanoma
Qian Sun, Nina Wang, Juliane Poelchen, Mareike Peter, Daniel Novak, Feyza Gül Özbay Kurt, Rebekka Bitsch, Huizi Wu, Yiman Wang, Sandra Pardo, Rui Han, Shibo Liu, Lidong Gong, Yuxin Zhang, Kilian Wistuba-Hamprecht, Viktor Umansky, Jochen Sven Utikal

Journal for ImmunoTherapy of Cancer Apr 2025, 13 (4) e010352; DOI: 10.1136/jitc-2024-010352

Main menu

Tumor microenvironment - TME

Pages

Log in using your username and password

Main menu

Log in using your username and password

You are here

Tumor microenvironment - TME

Pages