Adenosine

Prognostic significance and immune correlates of CD73 expression in renal cell carcinoma
Abhishek Tripathi, Edwin Lin, Wanling Xie, Abdallah Flaifel, John A Steinharter, Emily N Stern Gatof, Gabrielle Bouchard, Justin H Fleischer, Nieves Martinez-Chanza, Connor Gray, Charlene Mantia, Linda Thompson, Xiao X Wei, Marios Giannakis, Bradley A McGregor, Toni K Choueiri, Neeraj Agarwal, David F McDermott, Sabina Signoretti, Lauren C Harshman

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (2) e001467; DOI: 10.1136/jitc-2020-001467
Immunohistochemical scoring of CD38 in the tumor microenvironment predicts responsiveness to anti-PD-1/PD-L1 immunotherapy in hepatocellular carcinoma
Harry Ho Man Ng, Ren Yuan Lee, Siting Goh, Isabel Shu Ying Tay, Xinru Lim, Bernett Lee, Valerie Chew, Huihua Li, Benedict Tan, Sherlly Lim, Jeffrey Chun Tatt Lim, Bijin Au, Josh Jie Hua Loh, Sahil Saraf, John Edward Connolly, Tracy Loh, Wei Qiang Leow, Joycelyn Jie Xin Lee, Han Chong Toh, Fabio Malavasi, Ser Yee Lee, Pierce Chow, Evan W Newell, Su Pin Choo, David Tai, Joe Yeong, Tony Kiat Hon Lim

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000987; DOI: 10.1136/jitc-2020-000987
Small molecule AZD4635 inhibitor of A_2AR signaling rescues immune cell function including CD103⁺ dendritic cells enhancing anti-tumor immunity
Alexandra Borodovsky, Christine M Barbon, Yanjun Wang, Minwei Ye, Laura Prickett, Dinesh Chandra, Joseph Shaw, Nanhua Deng, Kris Sachsenmeier, James D Clarke, Bolan Linghu, Giles A Brown, James Brown, Miles Congreve, Robert KY Cheng, Andrew S Dore, Edward Hurrell, Wenlin Shao, Richard Woessner, Corinne Reimer, Lisa Drew, Stephen Fawell, Alwin G Schuller, Deanna A Mele

Journal for ImmunoTherapy of Cancer Jul 2020, 8 (2) e000417; DOI: 10.1136/jitc-2019-000417
Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade
Rui Yang, Samah Elsaadi, Kristine Misund, Pegah Abdollahi, Esten Nymoen Vandsemb, Siv Helen Moen, Anna Kusnierczyk, Geir Slupphaug, Therese Standal, Anders Waage, Tobias S Slørdahl, Torstein Baade Rø, Even Rustad, Anders Sundan, Carl Hay, Zachary Cooper, Alwin G Schuller, Richard Woessner, Alexandra Borodovsky, Eline Menu, Magne Børset, Anne Marit Sponaas

Journal for ImmunoTherapy of Cancer May 2020, 8 (1) e000610; DOI: 10.1136/jitc-2020-000610
Adenosine regulates radiation therapy-induced anti-tumor immunity
Erik Wennerberg, Noriko Kawashima, Sandra Demaria

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P378; DOI: 10.1186/2051-1426-3-S2-P378
On the mechanism of anti-CD39 immune checkpoint therapy
David Allard, Bertrand Allard, John Stagg

Journal for ImmunoTherapy of Cancer Feb 2020, 8 (1) e000186; DOI: 10.1136/jitc-2019-000186
Adenosine-generating ovarian cancer cells attract myeloid cells which differentiate into adenosine-generating tumor associated macrophages – a self-amplifying, CD39- and CD73-dependent mechanism for tumor immune escape
Itsaso Montalbán del Barrio, Cornelia Penski, Laura Schlahsa, Roland G. Stein, Joachim Diessner, Achim Wöckel, Johannes Dietl, Manfred B. Lutz, Michel Mittelbronn, Jörg Wischhusen, Sebastian F. M. Häusler

Journal for ImmunoTherapy of Cancer Dec 2016, 4 (1) 49; DOI: 10.1186/s40425-016-0154-9

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