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Research Article
Targeting interferon signaling and CTLA-4 enhance the therapeutic efficacy of anti-PD-1 immunotherapy in preclinical model of HPV+ oral cancer

Authors

  • Stephanie Dorta-Estremera Department of ImmunologyThe University of Texas MD Anderson Cancer Center 77030 Houston TX USA PubMed articlesGoogle scholar articles
  • Venkatesh L. Hegde Department of ImmunologyThe University of Texas MD Anderson Cancer Center 77030 Houston TX USA PubMed articlesGoogle scholar articles
  • Ravaen B. Slay Department of ImmunologyThe University of Texas MD Anderson Cancer Center 77030 Houston TX USA PubMed articlesGoogle scholar articles
  • Rachel Sun Oncology Research for Biologics and Immunotherapy TranslationThe University of Texas MD Anderson Cancer Center 77030 Houston TX USA PubMed articlesGoogle scholar articles
  • Ananta V. Yanamandra Department of ImmunologyThe University of Texas MD Anderson Cancer Center 77030 Houston TX USA PubMed articlesGoogle scholar articles
  • Courtney Nicholas Department of ImmunologyThe University of Texas MD Anderson Cancer Center 77030 Houston TX USA PubMed articlesGoogle scholar articles
  • Sita Nookala Department of ImmunologyThe University of Texas MD Anderson Cancer Center 77030 Houston TX USA PubMed articlesGoogle scholar articles
  • Gloria Sierra Department of ImmunologyThe University of Texas MD Anderson Cancer Center 77030 Houston TX USA The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences at Houston 77030 Houston TX USA PubMed articlesGoogle scholar articles
  • Michael A. Curran Department of ImmunologyThe University of Texas MD Anderson Cancer Center 77030 Houston TX USA The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences at Houston 77030 Houston TX USA PubMed articlesGoogle scholar articles
  • K. Jagannadha Sastry Department of ImmunologyThe University of Texas MD Anderson Cancer Center 77030 Houston TX USA The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences at Houston 77030 Houston TX USA PubMed articlesGoogle scholar articles
  1. ↵j 713-563-3304 jsastry{at}mdanderson.org
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Citation

Dorta-Estremera S, Hegde VL, Slay RB, et al
Targeting interferon signaling and CTLA-4 enhance the therapeutic efficacy of anti-PD-1 immunotherapy in preclinical model of HPV+ oral cancer
Journal for ImmunoTherapy of Cancer 2019;7:252. doi: 10.1186/s40425-019-0728-4

Publication history

  • Received July 15, 2019
  • Accepted September 2, 2019
  • First published September 18, 2019.
Online issue publication 
January 08, 2022

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© The Author(s). Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.