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  • Siglec-9+ tumor-associated macrophages delineate an immunosuppressive subset with therapeutic vulnerability in patients with high-grade serous ovarian cancer

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Immunotherapy biomarkers
Original research
Siglec-9+ tumor-associated macrophages delineate an immunosuppressive subset with therapeutic vulnerability in patients with high-grade serous ovarian cancer

Authors

  • Yiying Wang Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China PubMed articlesGoogle scholar articles
  • Mengdi He Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China PubMed articlesGoogle scholar articles
  • Chen Zhang Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China PubMed articlesGoogle scholar articles
  • Kankan Cao Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China PubMed articlesGoogle scholar articles
  • Guodong Zhang Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China PubMed articlesGoogle scholar articles
  • Moran Yang Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China PubMed articlesGoogle scholar articles
  • Yan Huang Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, China PubMed articlesGoogle scholar articles
  • Wei Jiang Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, ChinaDepartment of Gynecology, Obstetrics and Gynecology Hospital, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China PubMed articlesGoogle scholar articles
  • Haiou Liu Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Haiou Liu; liuhaiou{at}fudan.edu.cn; Dr Wei Jiang; Jiangwei_fckyy{at}163.com; Dr Yan Huang; huangyan19790315{at}163.com
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Citation

Wang Y, He M, Zhang C, et al
Siglec-9+ tumor-associated macrophages delineate an immunosuppressive subset with therapeutic vulnerability in patients with high-grade serous ovarian cancer
Journal for ImmunoTherapy of Cancer 2023;11:e007099. doi: 10.1136/jitc-2023-007099

Publication history

  • Accepted August 10, 2023
  • First published September 13, 2023.
Online issue publication 
September 13, 2023

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.