Neoadjuvant

Spatial transcriptomics highlights B cells as key contributors to a complete and durable response to chemo-immunotherapy in a patient with resectable NSCLC
Nicla Porciello, Filippo Gallina, Giuseppe Frisullo, Francesca Fusco, Lorenzo D’Ambrosio, Vittoria Balzano, Francesca De Nicola, Paolo Visca, Lorenza Landi, Federico Cappuzzo, Paola Nistico

Journal for ImmunoTherapy of Cancer May 2025, 13 (5) e011563; DOI: 10.1136/jitc-2025-011563
Neoadjuvant cobimetinib and atezolizumab with or without vemurafenib for stage III melanoma: outcomes and the impact of the microbiome from the NeoACTIVATE trial
Matthew S Block, Garth D Nelson, Jun Chen, Stephen Johnson, Lu Yang, Thomas James Flotte, Eric P Grewal, Robert R McWilliams, Lisa A Kottschade, Evidio Domingo-Musibay, Svetomir N Markovic, Anastasios Dimou, Heather N Montane, Mara A Piltin, Daniel L Price, Samir S Khariwala, Jane Yuet Ching Hui, Courtney L Erskine, Carrie A Strand, David Zahrieh, Haidong Dong, Tina J Hieken

Journal for ImmunoTherapy of Cancer Apr 2025, 13 (4) e011706; DOI: 10.1136/jitc-2025-011706
FDG-PET associations with pathological response and survival with neoadjuvant immunotherapy for melanoma
Li Zhou, Milton Jose Barros e Silva, Edward Hsiao, Zeynep Eroglu, Shahneen Sandhu, Igor Samoylenko, Serigne N Lo, Matteo S Carlino, George Au-Yeung, Maria Gonzalez, Andrew J Spillane, Thomas E Pennington, Kerwin F Shannon, Rony Kapoor, Elizabeth M Burton, Hussein A Tawbi, Rodabe N Amaria, Christian U Blank, João Pedreira Duprat, Rafaela Brito de Paula, David E Gyorki, Robyn P M Saw, Sydney Ch’Ng, Robert V Rawson, Richard A Scolyer, Ines Pires da Silva, Alexander C J van Akkooi, Georgina V Long, Alexander M Menzies

Journal for ImmunoTherapy of Cancer Mar 2025, 13 (3) e011483; DOI: 10.1136/jitc-2025-011483
Voxel-level radiomics and deep learning for predicting pathologic complete response in esophageal squamous cell carcinoma after neoadjuvant immunotherapy and chemotherapy
Zhen Zhang, Tianchen Luo, Meng Yan, Haixia Shen, Kaiyi Tao, Jian Zeng, Jingping Yuan, Min Fang, Jian Zheng, Inigo Bermejo, Andre Dekker, Dirk De Ruysscher, Leonard Wee, Wencheng Zhang, Youhua Jiang, Yongling Ji

Journal for ImmunoTherapy of Cancer Mar 2025, 13 (3) e011149; DOI: 10.1136/jitc-2024-011149
Phase 2 study of neoadjuvant durvalumab plus docetaxel, oxaliplatin, and S-1 with surgery and adjuvant durvalumab plus S-1 for resectable locally advanced gastric cancer
Yoon-Koo Kang, Hyung-Don Kim, Hyungwoo Cho, Young Soo Park, Jong Seok Lee, Min-Hee Ryu

Journal for ImmunoTherapy of Cancer Mar 2025, 13 (3) e010635; DOI: 10.1136/jitc-2024-010635
T-cell immune checkpoint inhibition plus hypomethylation for locally advanced HER2-negative breast cancer: a phase 2 neoadjuvant window trial of decitabine and pembrolizumab followed by standard neoadjuvant chemotherapy
Harry D Bear, Xiaoyan Deng, Dipankar Bandyopadhyay, Michael Idowu, Taylor M Jenkins, Maciej Kmieciak, Monique Williams, Giovanni Archer, Lindsey Gwaltney, Patrick Dillon, Daniel Flora, Daniel Stover, Andrew S Poklepovic, Mary Hackney, Masey Ross, Hetal Vachhani, Raphael Louie, Kandace P McGuire, Amelia Grover, Tasnim Rahman, Amber Hendrix

Journal for ImmunoTherapy of Cancer Feb 2025, 13 (2) e010294; DOI: 10.1136/jitc-2024-010294
Neoadjuvant anti-PD-1-based immunotherapy: evolving a new standard of care
Suzanne L Topalian, Drew M Pardoll

Journal for ImmunoTherapy of Cancer Jan 2025, 13 (1) e010833; DOI: 10.1136/jitc-2024-010833
Intratumoral and peritumoral radiomics of MRI predicts pathologic complete response to neoadjuvant chemoimmunotherapy in patients with head and neck squamous cell carcinoma
Jie Sun, Xuewei Wu, Ruhang Ma, Shuixing Zhang, Bin Zhang

Journal for ImmunoTherapy of Cancer Jan 2025, 13 (1) e011189; DOI: 10.1136/jitc-2024-011189
Neoadjuvant atezolizumab + chemotherapy for resectable NSCLC: 3-year clinical update of phase II clinical trial results and translational findings
Brian S Henick, Peter D Koch, Justin F Gainor, Mark M Awad, Codruta Chiuzan, Stephanie Izard, Yohanna Georgis, Samyukta Mallick, Robert F Garofano, Cheryl V Wong, Anjali Saqi, Jessica Grindheim, Katja Schulze, Joshua R Sonett, Naiyer A Rizvi, Benjamin Izar, Alison M Taylor, Catherine A Shu

Journal for ImmunoTherapy of Cancer Dec 2024, 12 (12) e009301; DOI: 10.1136/jitc-2024-009301
Multiomics reveals tumor microenvironment remodeling in locally advanced gastric and gastroesophageal junction cancer following neoadjuvant immunotherapy and chemotherapy
Zhi Ji, Xia Wang, Jiaqi Xin, Lijun Ma, Duo Zuo, Hongli Li, Lan Su, Xinze Lv, Shaohua Ge, Le Zhang, Yong Liu, Yanhui Zhang, Tingting Ding, Ting Deng, Yi Ba, Rui Liu

Journal for ImmunoTherapy of Cancer Dec 2024, 12 (12) e010041; DOI: 10.1136/jitc-2024-010041

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