Immunity

Increased coexpression of PD-L1 and TIM3/TIGIT is associated with poor overall survival of patients with esophageal squamous cell carcinoma
Peipei Wang, Yueyun Chen, Qingqin Long, Qing Li, Jiangfang Tian, Ting Liu, Yong Wu, Zhenyu Ding

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e002836; DOI: 10.1136/jitc-2021-002836
Dual checkpoint blockade of CD47 and PD-L1 using an affinity-tuned bispecific antibody maximizes antitumor immunity
Shih-Hsun Chen, Pawel K Dominik, Jessica Stanfield, Sheng Ding, Wenjing Yang, Nadia Kurd, Ryan Llewellyn, Jonathan Heyen, Carole Wang, Zea Melton, Thomas Van Blarcom, Kevin C Lindquist, Javier Chaparro-Riggers, Shahram Salek-Ardakani

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e003464; DOI: 10.1136/jitc-2021-003464
MYC suppresses STING-dependent innate immunity by transcriptionally upregulating DNMT1 in triple-negative breast cancer
Si-Yu Wu, Yi Xiao, Jin-Li Wei, Xiao-En Xu, Xi Jin, Xin Hu, Da-Qiang Li, Yi-Zhou Jiang, Zhi-Ming Shao

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002528; DOI: 10.1136/jitc-2021-002528
Homocitrullination of lysine residues mediated by myeloid-derived suppressor cells in the tumor environment is a target for cancer immunotherapy
Katherine W Cook, Wei Xue, Peter Symonds, Ian Daniels, Mohamed Gijon, David Boocock, Clare Coveney, Amanda K Miles, Sabaria Shah, Suha Atabani, Ruhul H Choudhury, Poonam Vaghela, Daisy Weston, Rachael L Metheringham, Victoria A Brentville, Lindy G Durrant

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e001910; DOI: 10.1136/jitc-2020-001910
Antiviral antibody responses to systemic administration of an oncolytic RNA virus: the impact of standard concomitant anticancer chemotherapies
Victoria Roulstone, David Mansfield, Robert J Harris, Katie Twigger, Christine White, Johann de Bono, James Spicer, Sophia N Karagiannis, Richard Vile, Hardev Pandha, Alan Melcher, Kevin Harrington

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002673; DOI: 10.1136/jitc-2021-002673
Oral SMEDDS promotes lymphatic transport and mesenteric lymph nodes target of chlorogenic acid for effective T-cell antitumor immunity
Jun Ye, Yue Gao, Ming Ji, Yanfang Yang, Zhaohui Wang, Baolian Wang, Jing Jin, Ling Li, Hongliang Wang, Xiaoyan Xu, Hengfeng Liao, Chunfang Lian, Yaqi Xu, Renjie Li, Tong Sun, Lili Gao, Yan Li, Xiaoguang Chen, Yuling Liu

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002753; DOI: 10.1136/jitc-2021-002753
Individualized genetic makeup that controls natural killer cell function influences the efficacy of isatuximab immunotherapy in patients with multiple myeloma
Haibo Sun, Thomas G Martin, John Marra, Denice Kong, Jonathon Keats, Sandrine Macé, Marielle Chiron, Jeffrey L Wolf, Jeffrey M Venstrom, Raja Rajalingam

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002958; DOI: 10.1136/jitc-2021-002958
Novel personalized cancer vaccine platform based on Bacillus Calmette-Guèrin
Erkko Ylösmäki, Manlio Fusciello, Beatriz Martins, Sara Feola, Firas Hamdan, Jacopo Chiaro, Leena Ylösmäki, Matthew J Vaughan, Tapani Viitala, Prasad S Kulkarni, Vincenzo Cerullo

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002707; DOI: 10.1136/jitc-2021-002707
Identification of neoantigen-reactive T lymphocytes in the peripheral blood of a patient with glioblastoma
Vid Leko, Gal Cafri, Rami Yossef, Biman Paria, Victoria Hill, Devikala Gurusamy, Zhili Zheng, Jared J Gartner, Todd D Prickett, Stephanie L Goff, Paul Robbins, Yong-Chen Lu, Steven A Rosenberg

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002882; DOI: 10.1136/jitc-2021-002882
PD-1⁺CXCR5⁻CD4⁺ Th-CXCL13 cell subset drives B cells into tertiary lymphoid structures of nasopharyngeal carcinoma
Jiang-Ping Li, Chang-You Wu, Ming-Yuan Chen, Shang-Xin Liu, Shu-Mei Yan, Yin-Feng Kang, Cong Sun, Jennifer R Grandis, Mu-Sheng Zeng, Qian Zhong

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002101; DOI: 10.1136/jitc-2020-002101

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