Antigen Presentation

Germline homozygosity and allelic imbalance of HLA-I are common in esophagogastric adenocarcinoma and impair the repertoire of immunogenic peptides
Maria Alejandra Garcia-Marquez, Martin Thelen, Eugen Bauer, Lukas Maas, Kerstin Wennhold, Jonas Lehmann, Diandra Keller, Miloš Nikolić, Julie George, Thomas Zander, Wolfgang Schröder, Philipp Müller, Ali M Yazbeck, Christiane Bruns, Roman Thomas, Birgit Gathof, Alexander Quaas, Martin Peifer, Axel M Hillmer, Michael von Bergwelt-Baildon, Hans Anton Schlößer

Journal for ImmunoTherapy of Cancer Apr 2024, 12 (4) e007268; DOI: 10.1136/jitc-2023-007268
Blocking senescence and tolerogenic function of dendritic cells induced by γδ Treg cells enhances tumor-specific immunity for cancer immunotherapy
Fusheng Si, Xia Liu, Yan Tao, Yuanqin Zhang, Feiya Ma, Eddy C Hsueh, Sidharth V Puram, Guangyong Peng

Journal for ImmunoTherapy of Cancer Apr 2024, 12 (4) e008219; DOI: 10.1136/jitc-2023-008219
Pyroptosis activates conventional type I dendritic cells to mediate the priming of highly functional anticancer T cells
Jordon M Inkol, Michael J Westerveld, Shayla G Verburg, Scott R Walsh, Jodi Morrison, Karen L Mossman, Sarah M Worfolk, Kaslyn LF Kallio, Noah J Phippen, Rebecca Burchett, Yonghong Wan, Jonathan Bramson, Samuel T Workenhe

Journal for ImmunoTherapy of Cancer Apr 2024, 12 (4) e006781; DOI: 10.1136/jitc-2023-006781
Novel peptide-based oncolytic vaccine for enhancement of adaptive antitumor immune response via co-engagement of innate Fcγ and Fcα receptors
Sara Feola, Firas Hamdan, Salvatore Russo, Jacopo Chiaro, Manlio Fusciello, Michaela Feodoroff, Gabriella Antignani, Federica D'Alessio, Riikka Mölsä, Virpi Stigzelius, Paolo Bottega, Sari Pesonen, Jeanette Leusen, Mikaela Grönholm, Vincenzo Cerullo

Journal for ImmunoTherapy of Cancer Mar 2024, 12 (3) e008342; DOI: 10.1136/jitc-2023-008342
Network-based screening identifies sitagliptin as an antitumor drug targeting dendritic cells
Ian-Ian Ng, Jiaqi Zhang, Tingzhong Tian, Qi Peng, Zheng Huang, Kaimin Xiao, Xiyue Yao, Lui Ng, Jianyang Zeng, Haidong Tang

Journal for ImmunoTherapy of Cancer Mar 2024, 12 (3) e008254; DOI: 10.1136/jitc-2023-008254
BCG hydrogel promotes CTSS-mediated antigen processing and presentation, thereby suppressing metastasis and prolonging survival in melanoma
Mirela Kremenovic, Alfred A Chan, Bing Feng, Lukas Bäriswyl, Steve Robatel, Thomas Gruber, Li Tang, Delphine J Lee, Mirjam Schenk

Journal for ImmunoTherapy of Cancer Jun 2022, 10 (6) e004133; DOI: 10.1136/jitc-2021-004133
Anticancer effects of ikarugamycin and astemizole identified in a screen for stimulators of cellular immune responses
Shuai Zhang, Liwei Zhao, Mengfei Guo, Peng Liu, Sijing Li, Wei Xie, Ai-Ling Tian, Jonathan G Pol, Hui Chen, Hui Pan, Misha Mao, Yumei Li, Laurence Zitvogel, Yang Jin, Oliver Kepp, Guido Kroemer

Journal for ImmunoTherapy of Cancer Jul 2023, 11 (7) e006785; DOI: 10.1136/jitc-2023-006785
Pattern recognition receptor agonists in pathogen vaccines mediate antitumor T-cell cross-priming
Mark Aleynick, Judit Svensson-Arvelund, Gvantsa Pantsulaia, Kristy Kim, Samuel A Rose, Ranjan Upadhyay, Michael Yellin, Henry Marsh, Daniel Oreper, Suchit Jhunjhunwala, Christine Carine Moussion, Miriam Merad, Brian D Brown, Joshua D Brody

Journal for ImmunoTherapy of Cancer Jul 2023, 11 (7) e007198; DOI: 10.1136/jitc-2023-007198
Immunosuppressive lncRNA LINC00624 promotes tumor progression and therapy resistance through ADAR1 stabilization
Qi Zhang, Bingqiu Xiu, Liyi Zhang, Ming Chen, Weiru Chi, Lun Li, Rong Guo, Jingyan Xue, Benlong Yang, Xiaoyan Huang, Zhi-Ming Shao, Shenglin Huang, Yayun Chi, Jiong Wu

Journal for ImmunoTherapy of Cancer Oct 2022, 10 (10) e004666; DOI: 10.1136/jitc-2022-004666
Targeting cathepsin B by cycloastragenol enhances antitumor immunity of CD8 T cells via inhibiting MHC-I degradation
Guoliang Deng, Lisha Zhou, Binglin Wang, Xiaofan Sun, Qinchang Zhang, Hongqi Chen, Ning Wan, Hui Ye, Xiaoqi Wu, Dongdong Sun, Yang Sun, Haibo Cheng

Journal for ImmunoTherapy of Cancer Oct 2022, 10 (10) e004874; DOI: 10.1136/jitc-2022-004874

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