antibody specificity

BTN1A1 is a novel immune checkpoint mutually exclusive to PD-L1
Young-Seung Kim, Seung-Hoon Lee, Andrew H Park, Chunai Wu, Bong-Ki Hong, Hyunjin Jung, Steven H Lin, Stephen S Yoo

Journal for ImmunoTherapy of Cancer Mar 2024, 12 (3) e008303; DOI: 10.1136/jitc-2023-008303
Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions
Roeland Lameris, Adam Shahine, Myrthe Veth, Bart Westerman, Dale I Godfrey, David Lutje Hulsik, Patricia Brouwer, Jamie Rossjohn, Tanja D de Gruijl, Hans J van der Vliet

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e007631; DOI: 10.1136/jitc-2023-007631
Bispecific binder redirected lentiviral vector enables in vivo engineering of CAR-T cells
Justin T Huckaby, Elisa Landoni, Timothy M Jacobs, Barbara Savoldo, Gianpietro Dotti, Samuel K Lai

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e002737; DOI: 10.1136/jitc-2021-002737
Evaluation of tumor antigen-specific antibody responses in patients with metastatic triple negative breast cancer treated with cyclophosphamide and pembrolizumab
Eric D Routh, Mark G Woodcock, Wolfgang Beckabir, Steven P Vensko, Jonathan S Serody, Benjamin G Vincent

Journal for ImmunoTherapy of Cancer Mar 2023, 11 (3) e005848; DOI: 10.1136/jitc-2022-005848
Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy
Lars Guelen, Thierry O Fischmann, Jerelyn Wong, Smita Mauze, Marco Guadagnoli, Nikolina Bąbała, Jozef Wagenaars, Veronica Juan, David Rosen, Winnie Prosise, Maurice Habraken, Imke Lodewijks, Danling Gu, Judith Stammen-Vogelzangs, Ying Yu, Jeanne Baker, David Lutje Hulsik, Lilian Driessen-Engels, Dan Malashock, Joost Kreijtz, Astrid Bertens, Evert de Vries, Astrid Bovens, Arne Bramer, Yiwei Zhang, Richard Wnek, Sean Troth, Elliot Chartash, Konstantin Dobrenkov, Svetlana Sadekova, Andrea van Elsas, Jason K Cheung, Laurence Fayadat-Dilman, Jannie Borst, Amy M Beebe, Hans Van Eenennaam

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e005049; DOI: 10.1136/jitc-2022-005049
Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy
Xin Liu, Yixiang Xu, Wei Xiong, Bingnan Yin, Yuqian Huang, Junjun Chu, Changsheng Xing, Chen Qian, Yang Du, Tianhao Duan, Helen Y Wang, Ningyan Zhang, John S. Yu, Zhiqiang An, Rongfu Wang

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e004035; DOI: 10.1136/jitc-2021-004035
Generalizable design parameters for soluble T cell receptor-based T cell engagers
Karen J Froning, Arlene Sereno, Flora Huang, Stephen J Demarest

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e004281; DOI: 10.1136/jitc-2021-004281
Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8⁺ T cell immunity to reject ‘cold’ tumors
Monika Semmrich, Jean-Baptiste Marchand, Laetitia Fend, Matilda Rehn, Christelle Remy, Petra Holmkvist, Nathalie Silvestre, Carolin Svensson, Patricia Kleinpeter, Jules Deforges, Fred Junghus, Kirstie L Cleary, Mimoza Bodén, Linda Mårtensson, Johann Foloppe, Ingrid Teige, Eric Quéméneur, Björn Frendéus

Journal for ImmunoTherapy of Cancer Jan 2022, 10 (1) e003488; DOI: 10.1136/jitc-2021-003488
Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer
Tianhang Zhai, Chao Wang, Yifeng Xu, Weifeng Huang, Zhijun Yuan, Tao Wang, Shuang Dai, Shaogang Peng, Tuling Pang, Wenchao Jiang, Yuhua Huang, Yuefeng Zou, Yingda Xu, Joanne Sun, Xinjiang Gong, Jinping Zhang, Andy Tsun, Bin Li, Xiaoniu Miao

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002131; DOI: 10.1136/jitc-2020-002131
Immunotherapy using IgE or CAR T cells for cancers expressing the tumor antigen SLC3A2
Giulia Pellizzari, Olivier Martinez, Silvia Crescioli, Robert Page, Ashley Di Meo, Silvia Mele, Giulia Chiaruttini, Jan Hoinka, Ihor Batruch, Ioannis Prassas, Melanie Grandits, Jacobo López-Abente, Eva Bugallo-Blanco, Malcolm Ward, Heather J Bax, Elise French, Anthony Cheung, Sara Lombardi, Mariangela Figini, Katie E Lacy, Eleftherios P Diamandis, Debra H Josephs, James Spicer, Sophie Papa, Sophia N Karagiannis

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002140; DOI: 10.1136/jitc-2020-002140

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