Treatment summary and response
Patient | Duration of TVEC (months) | # of injections | Total injected dose of TVEC (mL) | Total # lesions injected | Imiquimod added | Outcome | Follow-up time (Months) |
1 | 5 | 12 | 34.2 | 20 | After cycle 2 | Systemic and locoregional progression after 12 injections | 6 |
2 | 9 | 20 | 16.1 | 15 | After cycle 13 | CR, clear of any disease at 3 years post-T-VEC | 26 |
3 | 6 | 13 | 11.5 | 9 | After cycle 1 | CR, clear of any disease at 4 months post-T-VEC | 8 |
4 | 4 | 8 | 29.9 | 11 | After cycle 3 | CR, clear of any disease at 5 years post-T-VEC | 51 |
5 | 6 | 14 | 8.7 | 12 | After cycle 4 | CR, systemic progression after 10 months post-T-VEC | 16 |
CR, complete response; T-VEC, talimogene laherparepvec.