Binding kinetics of CD3xCD33 bispecific antibodies to human CD33
| ka (1/Ms) | kd (1/s) | ka2 (1/s) | kd2 (1/s) | KD (M) | |
| BC269 | 7.84E+05 | 6.58E−04 | 3.12E−03 | 4.30E−04 | 1.02E−10 |
| BC133 | 9.85E+05 | 7.97E−03 | 2.06E−03 | 9.02E−04 | 2.47E−09 |
| BC275 | 3.37E+05 | 1.36E−03 | 3.72E−03 | 7.13E−04 | 6.49E−10 |
ka2, equilibrium association constant 2; ka, equilibrium association constant; kd, equilibrium dissociation constant; kd2, equilibrium dissocation constant 2; KD (M), equilibrium dissociaiton constant molarity.